Formulation, preparation and characterization of a bone adhesive

Abstract

An adhesive capable of fixing small bone fragments is an attractive alternative to orthopedic surgeons. To date no suitable bone adhesive meets all the requirements for clinical use. This experimental study was directed to evaluate two different biopolymers (chitosan and alginate) with the potential to be used as adhesives for bones due to their biocompatibility and degradability [2]. Results were compared with Kryptonite® a commercial bone cement with adhesive properties that has shown promising in vivo results and has FDA approval.