Fast phosphorus MR spectroscopic imaging of human brain using compressed sensing

Abstract

This study aims at acquiring and reconstructing compressed sensing accelerated phosphorus MR spectroscopic imaging (31P-MRSI) of human brain in vivo. Accelerated 31P-MRSI volunteer data were acquired using pulse and acquire with compressed sensing at 3T. k-space data was randomly undersampled for a five fold scan time reduction while preserving the central portion, and reconstructed using three dimensional compressed sensing algorithm. This study showed that compressed sensing method could be applied for faster 31P MR spectroscopic imaging of human brain at 3T.