Endothelail and Stress Index as One of New Prognostic Determinants of COVID- 19 Severity‎‎

Abstract

stay, and intensive care unit (ICU) admission. Complete blood picture with differential count, C-reactive protein, ferritin, D-Dimer, liver and renal function tests, lactate dehydrogenase, cardiac markers, EASIX, chest CT, ECG, and Echo were done. Results: EASIX along with D-Dimer and ferritin showed statistically significant sensitivity and specificity when analysed as predictors for COVID-19 mortality, need for ICU admission and mechanical ventilation, while lymphocyte/monocyte ratio (LMR) showed statistically significant sensitivity and specificity only for COVID-19 mortality and need for ICU admission. D-Dimer had the highest overall accuracy, followed by ferritin, EASIX, and the lowest accuracy appear in LMR. Conclusion and recommendation: Because of its strong correlation with COVID-19 mortality, ESAIX should be added as a new biomarker to the existing set of biomarkers linked to poor prognosis namely D-Dimer and ferritin .