THE USE OF ENDONASAL ELECTROPHORESIS WITH MEXIDOL IN COMBINATION WITH ACUPUNCTURE IN THE TREATMENT OF PATIENTS WITH POST-COVID ANOSMIA

M. Al-Zamil, M. N. Puzin, A. Shulaev, E. Kiparisova, Alexander V. Lubimov, T. Y. Shilova, Lia SH. Ramazanova, S. M. Makkaeva, Alexander P. Skorokhodov, Nina A. Gunter
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Abstract

Introduction. A change or lack of odor in patients after suffering from Covid-19 caused the development of serious disturbances in appetite and nutrition, which led to a decrease in body weight and a deterioration in the function of the digestive system as a whole, followed by alimentary damage to internal organs. Aim. To study the effectiveness of the combined use of endonasal electrophoresis and acupuncture in the treatment of patients with post-covid anosmia. Materials and methods: 30 patients with a confirmed diagnosis of COVID-19 were under our supervision. All patients suffered from post-covid anosmia. 15 patients underwent exclusively drug therapy (control group) and 15 patients, in addition to drug therapy, underwent a course of endonasal electrophoresis of 5% Mexidol solution and acupuncture. All patients underwent testing of olfactory nerve function with the Sniffin ‘Sticks test before and after treatment. Results and its discussions: it was found that the use of endonasal electrophoresis in combination with acupuncture significantly enhances the effectiveness of drug therapy in improving the parameters of the olfactory nerve in the threshold test by 143.5% (p <0.01), the discriminatory test by 129.5% (p <0, 01), the identification test by 184.5% (p <0.01) and by the total number of points by 148.7% (p <0.01). Conclusion: High efficiency of combined use of endonasal electrophoresis of 5% Mexidol solution and acupuncture in the treatment of patients with post-covid anosmia was detected. This method of treatment increases the effectiveness of drug therapy by 1.5 times.
美西多鼻内电泳联合针刺治疗新冠肺炎后嗅觉缺失
介绍。新冠肺炎患者的气味改变或缺乏会导致食欲和营养严重紊乱,从而导致体重下降和整个消化系统功能恶化,随后对内脏器官造成消化道损伤。的目标。目的:探讨鼻内电泳联合针刺治疗新冠肺炎后嗅觉缺失的疗效。材料和方法:我们对30例确诊为COVID-19的患者进行监测。所有患者均出现新冠肺炎后嗅觉缺失。15例患者接受纯药物治疗(对照组),15例患者在接受药物治疗的同时,接受5%美西多溶液鼻内电泳和针灸治疗。所有患者在治疗前后均采用嗅探棒试验检测嗅觉神经功能。结果及讨论:经鼻内窥镜电泳与针刺联合应用,对嗅神经阈值测试、鉴别测试、鉴别测试、总穴位数的改善效果分别提高143.5% (p <0.01)、129.5% (p <0.01)、184.5% (p <0.01)、148.7% (p <0.01)。结论:5%美西多溶液鼻内电泳联合针刺治疗新冠肺炎后嗅觉障碍疗效显著。这种治疗方法使药物治疗的效果提高1.5倍。
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