Investigating How Social and Economic Geography Affect ß-thalassemia's spread

Altug AkayI, Andrei Dragomir, A. Yardimci, D. Canatan, Dr. Akif Yesilipek, B. Pogue
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Abstract

beta-thalassemia, an anemic genetic disorder, remains a significant global health issue, especially in the era of globalization where healthcare, economics, and education are more tightly interconnected. Although previous studies focused on the medical aspect of beta-thalassemia and the affects of consanguineous marriages, we investigated what affects the socio-economic geography of beta-thalassemia and how it affects the spread rate using self-organizing maps (SOM) and Sammon mapping. We converted data generated from questionnaires into numerical variables to facilitate the subsequent analysis of how certain variables contribute to beta-thalassemia's spread. We expected a strong correlation among variables (current education and financial status, information availability, neighborhood prevention programs, and treatment affordability). Only 28% of the population contained both high education and high income, thus had the highest awareness. We studied the mapped data and identified relevant variables corresponding to factors affecting the spread rate of beta-thalassemia. We concluded that education directly correlates to beta-thalassemia's spread rate. Education created a ripple effect, affecting other variables. The data supports the idea that a more educated population, combined with aggressive prevention and treatment programs should prevent the spread of beta-thalassemia.
调查社会和经济地理如何影响ß-地中海贫血的传播
地中海贫血是一种遗传性贫血,仍然是一个重大的全球健康问题,特别是在全球化时代,医疗保健、经济和教育之间的联系更加紧密。虽然以前的研究主要集中在-地中海贫血的医学方面和近亲婚姻的影响,但我们使用自组织地图(SOM)和Sammon地图调查了影响-地中海贫血的社会经济地理因素及其如何影响传播率。我们将问卷调查产生的数据转换为数值变量,以便于后续分析某些变量如何导致-地中海贫血的传播。我们期望变量之间有很强的相关性(当前教育和经济状况、信息可得性、社区预防计划和治疗负担能力)。只有28%的人同时拥有高等教育和高收入,因此他们的意识是最高的。我们研究了绘制的数据,并确定了影响β -地中海贫血传播率的相关变量。我们得出结论,教育程度与地中海贫血的传播率直接相关。教育产生了连锁反应,影响了其他变量。这些数据支持这样一种观点,即受教育程度更高的人群,结合积极的预防和治疗方案,应该可以防止-地中海贫血的传播。
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