CLINICAL CASE OF CRYPTOCOCCAL MENINGITIS IN A LIVER TRANSPLANT PATIENT

L. Boyanova, Z. Ivanova
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Abstract

The incidence of infections caused by Cryptococcus neoformans has increased significantly in recent years, especially in the settings of immune deficiency  (HIV infection transplantation, etc.). Most often after inhalation of spores   dissemination of yeast to the brain parenchyma   occurs, leading to meningitis (meningo-encephalitis). Our clinical case,  is a patient with cryptococcal meningitis after liver   transplantation  , who died despite the onset of antifungal therapy. This is further evidence of the severe prognosis of CNS cryptococcosis, especially in immunocompromised patients.
肝移植患者隐球菌性脑膜炎1例临床分析
近年来,由新型隐球菌引起的感染的发生率显著增加,特别是在免疫缺陷的情况下(HIV感染移植等)。最常见的是孢子吸入后酵母传播到脑实质,导致脑膜炎(脑膜脑炎)。我们的临床病例是一例肝移植后隐球菌性脑膜炎患者,尽管开始了抗真菌治疗,但仍死亡。这进一步证明了中枢神经系统隐球菌病的严重预后,特别是免疫功能低下的患者。
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