Characteristics of Polarized Light Pattern in Variation of Material's Density Values for Cancer Cell Characterization Method

Abstract

Biomaterial characterization through the use of polarized light has had a long history of application and improvement. Angle of polarization (AOP) sensor was used to measure the polarized light patterns. The main objective of this article is to investigate the capabilities of AOP sensor and determine whether it is reliable and consistent in distinguishing physical properties of biomaterials. The physical property of material chosen as a variable in this study is density. In this study, a salt solution is used as a sample on which to model the biomaterial. The density of salt solution is varied between 1.006 g/ml and 1.201 g/ml. The characteristics of the angle of polarization (AOP) of incident rays with wavelengths of 483–595 nm, 495–570 nm, 590–620 nm, 620–750 nm were investigated. Based on the results obtained, the AOP measured via AOP sensor is increased with the increment of density value of salt solutions. The pattern of AOP showed the linear line increment between densities of 1.006 to 1.169 g/ml. The AOP reading showed the sharp increment after the density 1.169 g/ml. This results showed that the AOP can have a specific pattern for specific value of density. This finding shows that the AOP pattern can be used to investigate the changes in the density of the sample, and thus has the potential to be used for cancer cell characterization in medical applications.