CHOICE OF A RECONSTRUCTION METHOD FOR POSITRON-EMISSION ECG-GATED STUDIES AND ITS EFFECT ON CALCULATED VOLUMETRIC PARAMETERS OF THE LEFT VENTRICULAR FUNCTION AND VISUAL IMAGE QUALITY

Mosin D.Yu., Kondakov A.K., Moshkova E.N., Kharina D.S., Khasanboev S.G., Znamenskiy I.A., Butenko A.V.
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Abstract

Ischemic heart disease is one of the leading causes of mortality in the Russian Federation. Timely diagnosis of this condition allows you to determine the optimal treatment tactics. Positron emission tomography with 18-fluorodeoxyglucose is a method for verifying viable cardiac tissue in patients with myocardial infarction. The methods used for the reconstruction of positron emission tomograms can affect the quantitative indicators of the contractile function of the myocardium. Materials and methods. The study retrospectively included 12 patients who underwent PET/CT with 18-fluorodeoxyglucose, the results of which were reconstructed using filtered back projection methods and iterative reconstruction, with ECG synchronization and division of ECG R-R intervals into 8, 10 and 16 frames. The obtained images were evaluated visually by two radiologists, and the quantitative parameters characterizing the contractile function of the left ventricular myocardium were compared in pairs. Results. There were no significant differences in the assessment of quantitative indicators such as end-systolic and diastolic volumes, stroke volume and ejection fraction. However, the iterative reconstruction results show less data scatter than the filtered back projection reconstruction method. In visual analysis, the best quality of reconstructions by iterative methods is noted. Conclusions. Thus, the recommended method for both visual analysis and quantification is iterative reconstruction, regardless of the number of timing windows used. A spread in the number of used reconstructed fragments of the cardiac cycle in the range of 8-16, commonly used in clinical practice, can be recommended.
正电子发射门控研究重建方法的选择及其对左心室功能计算体积参数和视觉图像质量的影响
缺血性心脏病是俄罗斯联邦死亡的主要原因之一。及时诊断这种情况可以让你确定最佳的治疗策略。18-氟脱氧葡萄糖正电子发射断层扫描是一种验证心肌梗死患者存活心脏组织的方法。正电子发射层析成像的重建方法会影响心肌收缩功能的定量指标。材料和方法。本研究回顾性纳入12例接受18-氟脱氧葡萄糖PET/CT检查的患者,采用滤波反投影法和迭代重建方法重建结果,心电同步,并将心电R-R间隔划分为8、10和16帧。获得的图像由两名放射科医生进行目测评估,并对表征左心室心肌收缩功能的定量参数进行两两比较。在收缩期末和舒张期容积、卒中容积和射血分数等定量指标的评估上,两组无显著差异。然而,迭代重建的结果表明,与滤波后的反投影重建方法相比,数据散射较小。在视觉分析中,迭代法的重建质量最好。因此,对于可视化分析和量化,推荐的方法是迭代重建,而不管使用的时间窗口的数量。可推荐临床常用的心脏周期重构片段在8-16个范围内使用。
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