FUNCTIONAL RECOVERY OF RADIAL ARTERY CONDUIT FOR CORONARY ARTERY BYPASS GRAFTING

Ripp Tm, D. Kondratieva, S. Afanasiev, E. Muslimova, B. Kozlov, Mordovin Vf
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引用次数: 1

Abstract

The authors have studied the effect of lercanidipine on the functional status of radial artery used as conduit for CABG in patients with coronary artery stenosis. Endothelium-dependent vasodilation (ΔD) was evaluated preoperatively by using duplex ultrasound. Patients were divided into groups I and II with ΔD≥8% and ΔD<8%, respectively. Group II was divided into groups IIA (lercanidipine) and IIB (control). Mechanical force of isolated arterial segments was initially lower in group I. Preoperative treatment with lercanidipine (2.5–5 mg/kg for 5–7 days) led to a significant increase in endothelium-dependent vasodilation and decrease in tone of isolated arterial segments. Preoperative treatment with lercanidipine effectively preserved dilatational properties of arterial conduit.
冠状动脉旁路移植术中桡动脉导管功能恢复
作者研究了雷卡尼地平对冠状动脉狭窄患者冠状动脉冠脉搭桥术桡动脉导管功能状态的影响。术前采用双工超声评估内皮依赖性血管舒张(ΔD)。将患者分为ΔD≥8%组和ΔD<8%组。II组分为IIA组(莱卡尼地平)和IIB组(对照组)。ⅰ组离体动脉段机械力较低,术前给予雷卡尼地平(2.5 ~ 5mg /kg, 5 ~ 7天)治疗,内皮依赖性血管舒张明显增加,离体动脉段张力明显降低。术前应用雷卡尼地平有效地保持了动脉导管的扩张特性。
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