Study of skeletal muscle behavior by PET/MRI

David García Juan, S. Trombella, B. Delattre, Y. Seimbille, O. Ratib
{"title":"Study of skeletal muscle behavior by PET/MRI","authors":"David García Juan, S. Trombella, B. Delattre, Y. Seimbille, O. Ratib","doi":"10.1109/BHI.2014.6864304","DOIUrl":null,"url":null,"abstract":"Increasingly aging population is leading to higher prevalence of musculoskeletal disorders and related muscular dysfunctions, requiring new types of functional investigations in daily clinical practice. Emerging non-invasive imaging techniques, such as hybrid PET/MRI, allow to visualize and to analyze the human body from the anatomical and metabolic point of view in a single scanning session. We aim to investigate both muscle anatomical behaviour by MRI and exercise-related changes in muscle functionality by PET/MRI and [11C]Acetate, in view to develop a model of normal resting and exercised muscle. The static and dynamic PET and MRI acquisition protocols that we developed are described. Dedicated processing techniques are defined for the generation and visualization of 4D datasets, including both anatomical and metabolic acquired data. This paper reports the technical framework and methodological approach developed as a first step in our research. Experimental data are being collected and will be included in future validation studies.","PeriodicalId":177948,"journal":{"name":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","volume":"68 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BHI.2014.6864304","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

Abstract

Increasingly aging population is leading to higher prevalence of musculoskeletal disorders and related muscular dysfunctions, requiring new types of functional investigations in daily clinical practice. Emerging non-invasive imaging techniques, such as hybrid PET/MRI, allow to visualize and to analyze the human body from the anatomical and metabolic point of view in a single scanning session. We aim to investigate both muscle anatomical behaviour by MRI and exercise-related changes in muscle functionality by PET/MRI and [11C]Acetate, in view to develop a model of normal resting and exercised muscle. The static and dynamic PET and MRI acquisition protocols that we developed are described. Dedicated processing techniques are defined for the generation and visualization of 4D datasets, including both anatomical and metabolic acquired data. This paper reports the technical framework and methodological approach developed as a first step in our research. Experimental data are being collected and will be included in future validation studies.
骨骼肌行为的PET/MRI研究
人口老龄化加剧导致肌肉骨骼疾病和相关肌肉功能障碍的患病率上升,在日常临床实践中需要新型的功能调查。新兴的非侵入性成像技术,如PET/MRI混合成像技术,可以在一次扫描中从解剖学和代谢的角度对人体进行可视化和分析。我们的目标是通过MRI研究肌肉解剖行为,通过PET/MRI和[11C]Acetate研究肌肉功能的运动相关变化,以建立正常休息和运动肌肉的模型。描述了我们开发的静态和动态PET和MRI采集协议。为生成和可视化4D数据集(包括解剖和代谢获得的数据)定义了专用处理技术。本文报告了作为我们研究的第一步而开发的技术框架和方法方法。正在收集实验数据,并将纳入未来的验证研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信