A multicompartmental model for simulation of soluble gas exchange in the lungs

A. Ritter, C. Varadhan, D. Kristol
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Abstract

A lung model for soluble gas exchange that will allow quantitative estimation of the pharmacokinetics of inhaled anesthetic agents is described. This lung model is coupled to a whole body hemodynamic model given by B. Pu/spl acute/ramic (M.S. thesis, New Jersey Inst. of Techn., 1992). The partial pressure of a soluble gas in the pulmonary artery (PPA), the integrated average pulmonary capillary pressure (PPC), and the partial pressure of gas in the pulmonary vein (PPV) system for one set of simulation values are shown. The partial pressures of the gas in the three lung capillary zones are also given.<>
模拟肺部可溶气体交换的多室模型
一个肺模型的可溶性气体交换,将允许定量估计吸入麻醉剂的药代动力学描述。该肺模型与新泽西理工大学b.p u/spl急性/急性期(ms . thesis, New Jersey institute of technology)给出的全身血流动力学模型耦合。, 1992)。给出了一组模拟值下的肺动脉溶气分压(PPA)、肺毛细血管综合平均压力(PPC)和肺静脉系统气体分压(PPV)。同时给出了三个肺毛细血管区的气体分压。
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