Impact of Membrane Resistance on Width and Amplitude of Spikes in Different Injected Currents in One Spiking Neural Model

Abstract

Neurons in the brain as the elementary processing units and nervous system play a key role. If a neuron gets a proper stimulus, it produces action potentials (spikes) that are transferred along its axon. Reaching the end of the neuron, other neurons or muscle cells may be activated [1]. The effect of neural morphology along with thickness of dendrites and passive electrical parameters on the spikes width and amplitude can be investigated by analytical and numerical investigations of spiking models. The impact of mentioned proper stimulus may be degraded by passing time. In this paper, it is tried to add the effective parameter ’membrane resistance’ in well-known Hodgkin-Huxley model with four dimensions to compare several outputs due to changing resistance and various injected current. The goal of this paper has been to measure spikes changes or even how to determine current threshold when resistance is not constant (non-linear time dependant) result of different factors.