Has Kisspeptin found a place to be a biomarker in the differentiation of viability of early pregnancy-a short commentary

Abstract

in hypothalamic amenorrhea initially. In previous studies it has been found that levels of Kp increase as the pregnancy develops and there is significant but weak correlation (r=0.46;p<0.005) between Kp54 and progesterone(P) levels.4 LH also gets increased with kisspeptin administration.5 Importance of LH and HCG to corpus luteum function is also well established. It is well known that using HCG in the luteal phase improves corpus luteum(CL) function and outcome in women with unexplained recurrent loss.6 Now kp-54 has been emerging as a biomarker for the discrimination of viable pregnancy from cases of spontaneous abortion in view of its potential regulatory role in trophoblast function and placentation.7,8