Secondary Infertility of the Couple: Epidemiological and Clinical Aspects of Patients at the General Hospital of Loandjili in Pointe Noire (Republic of the Congo)

Mokoko Jules César, Eouani Max Lévy Eméry, Buambo Gauthier Régis Jostin, Potokoue Mpia Samantha Nuelly, Itoua Clautaire, Iloki Léon Hervé
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Abstract

Objective: Describe the epidemiological and clinical aspects and report the paraclinical anomalies in the case of secondary infertility of the couple to the General Hospital of Loandjili. Method: Descriptive cross-sectional study, conducted from January 1, 2017 to December 31, 2018, comprehensively including all the patients who consulted for secondary infertility, as defined by the World Health Organization (WHO). This involved the inability of a previously conceived couple to re-conceive and carry a pregnancy to term after a year or more of regular, unprotected sex for women under 35 years and after six months for women over 35. The presence of the spouse was required in the event of an abnormal spermogram. The variables studied were socio-demographic, reproductive, clinical, and para-clinical. Results: The couple's secondary infertility represented 25% of all Gynecology consultations (98/392). The patients were on average 34.7 ± 1.5 years old with a predominance of the 31 to 40 years age group. They were paucigest (2.8 ± 0.1) and pauciparous (1.8 ± 0.1), consulting for infertility with a median duration of 5 years. Their spouse had an average age of 41.3 ± 3.6 years. Clinically, 20% of patients had a history of pelvic surgery for benign gynecological disease. Biologically, genital infections were predominant (73.4%), most often associated with abnormalities of the cervical mucus (59.2%) and post coital test (37%). Regarding the spouse, spermogram abnormalities were noted in 45% of cases and dominated by oligozoospermia (35%). In 65% of cases, the antral follicle count was insufficient in 22% and zero in 6.2%. The indications for medically assisted procreation (MAP) were of the order of 20%, while only half had been able to benefit from this service abroad with six pregnancies including four deliveries with live children. Conclusion: Medically assisted procreation would be an alternative in the management approaches. Thus, efforts must be made to provide an appropriate response to that whose treatment requires this indication.
夫妇继发性不孕症:黑角(刚果共和国)Loandjili总医院患者的流行病学和临床情况
目的:描述该夫妇继发性不孕症的流行病学和临床情况,并向罗兰吉里总医院报告临床旁异常情况。方法:描述性横断面研究,于2017年1月1日至2018年12月31日进行,全面纳入世界卫生组织(who)定义的所有继发性不孕症患者。这涉及到35岁以下的女性在一年或更长时间的定期无保护的性行为后,以及35岁以上的女性在6个月后,先前怀孕的夫妇无法再次怀孕并将妊娠足月。在精子图异常的情况下,需要配偶在场。研究的变量包括社会人口学、生殖、临床和准临床。结果:这对夫妇继发性不孕症占所有妇科咨询的25%(98/392)。患者平均年龄34.7±1.5岁,以31 ~ 40岁年龄组为主。最多囊(2.8±0.1)和最多囊(1.8±0.1),咨询不孕症,中位持续时间5年。配偶平均年龄41.3±3.6岁。临床上,20%的患者有盆腔手术治疗良性妇科疾病的病史。生物学上,生殖器感染占主导地位(73.4%),最常与宫颈粘液异常(59.2%)和性交后检查(37%)相关。在配偶方面,45%的病例出现精子图异常,以少精症为主(35%)。在65%的病例中,窦卵泡计数不足的占22%,零的占6.2%。医疗辅助生殖(MAP)的适应症约为20%,而只有一半的人能够从国外的这项服务中受益,其中有6次怀孕,包括4次活产。结论:医学辅助生殖是一种可行的治疗方法。因此,必须努力提供适当的反应,其治疗需要这一指征。
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