Transarterial Embolization Treatment of Sacral Tumors

D. Anghelescu, E. Popescu, A. Cursaru, A. Dimitriu, R. Ene, C. Cîrstoiu
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Abstract

Abstract Objectives. Sacral tumors represent about 1-4,3% of all bone tumors. They typically present with an abundance of blood vessels. Due to their anatomical localization, they are hard to approach surgically. Thus, a presurgical neoadjuvant therapy is indicated. The preoperative angiography with the embolization of the nutritive arteries decreases the perioperative blood loss and the symptomatology, and even decreases the volume of the tumors that cannot be surgically approached. Materials and methods. The principle of embolization consists in the targeting of the nutritive tumoral artery and in obturating it with embolic agents (polyvinyl alcohol, embospheres, etc.) through selective catheterization under angiographic control. The biopsy of the tumor is essential for certain diagnosis. The histological type of the tumor and the degree of differentiation influence the tumor’s physiopathology and often influence the therapeutic decision regarding its degree or recurrence. In some cases in which the tumor’s degree of extension increases the surgical risk, serial embolization can be used as a primary method of treatment. Because of the late onset symptomatology, when they are discovered they are extended and the degree of invasion in adjacent tissues is so high that it requires en bloc resection with nerve root sacrifice to assert complete excision and low recurrence rates. Results. The patients who undergo surgical treatment usually bleed, and the perioperative blood loss and the need for blood transfusion volumes were halved in the cases in which presurgical transarterial embolization was performed. Conclusions. Transarterial embolization of sacral tumors is a procedure indicated as a neoadjuvant presurgical therapy to decrease the blood loss risks and for the tumors that cannot be surgically removed it is used in the palliative treatment to reduce symptomatology.
经动脉栓塞治疗骶骨肿瘤
抽象的目标。骶骨肿瘤约占所有骨肿瘤的1-4,3%。它们通常表现为血管丰富。由于它们的解剖定位,它们很难通过手术接近。因此,手术前的新辅助治疗是指。术前血管造影与营养动脉栓塞减少围手术期出血量和症状,甚至减少无法手术接近的肿瘤体积。材料和方法。栓塞的原理是瞄准肿瘤的营养动脉,在血管造影的控制下,通过选择性插管,用栓塞剂(聚乙烯醇、栓子等)将其封闭。肿瘤的活组织检查对某些诊断是必要的。肿瘤的组织学类型和分化程度影响肿瘤的生理病理,并常常影响其复发程度的治疗决策。在某些病例中,肿瘤的扩展程度增加了手术风险,连续栓塞可以作为主要的治疗方法。由于发病较晚,当发现时已扩展,且侵犯邻近组织的程度很高,需要整体切除并牺牲神经根以保证完全切除,复发率低。结果。手术治疗患者多出血,术前经动脉栓塞可使围术期出血量和输血需要量减少一半。结论。经动脉栓塞治疗骶骨肿瘤是一种新辅助手术前治疗方法,可减少失血风险,对于不能手术切除的肿瘤,可用于姑息治疗,以减少症状。
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