Organic Nanoparticles Using Microfluidic Technology for Drug‐Delivery Applications

Abstract

The sections in this article are Introduction Batch Synthesis of Organic Nanoparticles Specifications of Reactors: Macroscale versus Microscale Syntheses Properties and Application of Organic Nanoparticles for Drug Delivery Microfluidic Synthesis of Organic Nanoparticles Overview: Unique Features of Microfluidic Reactors for the Controlled Synthesis of Organic Nanoparticles Microfluidic Reactors for Organic Nanoparticles Emulsions Nanoprecipitation Liposomes Controlled Operating Parameters of Microfluidic Reactors Flow Velocity, Microfluidic Dimension, and Mixing Time Mixing Time, Aggression Time, and the Damkohler Number Synthetic Operations Micromixing Online Process of Various Reactants Thermal Control and Heat Transfer Spatial and Temporal Kinetic Control Self-Assembly Mechanism and Competitive Reaction Microfluidic-Related Organic Nanoparticles for Drug Delivery Drug Encapsulation and Release Stimuli-Responsive Release Nanomedicine Delivery to Target Cells Conclusions and Prospective Study Materials, Design, and Fabrication High-Throughput Microfluidic Processes Controlled Synthesis of Organic Nanoparticles Spatial and Temporal Kinetics Investigation of Nanoparticles Keywords: nanomaterials; microfluidics; controlled synthesis; organic nanoparticles; nanomedicine delivery