The behaviour and treatment outcomes of paediatric hemangiomas

Gowri Balakrishnana, K. Balasundaram, M. Gunasekaran, Karthik Shunmugavelu
{"title":"The behaviour and treatment outcomes of paediatric hemangiomas","authors":"Gowri Balakrishnana, K. Balasundaram, M. Gunasekaran, Karthik Shunmugavelu","doi":"10.54936/haoms223155164","DOIUrl":null,"url":null,"abstract":"Aim: Infantile hemangiomas are the most common vascular tumours of infancy, affecting up to 12% of infants by the first year of life. The main aim of this study is to present the best treatment modality based on the behaviour of hemangiomas in paediatric population and their pattern of progression or regression with age and in response to intralesional steroids and sclerosing agents administered, along with the rate of recurrence in cases where surgical intervention was done. Materials and methods: A total of 25 patients were in- cluded in this study based on inclusion and exclusion cri- teria. The injections (Kenacort /Kenalog, as intralesional injection) were administered at monthly intervals and patients were reviewed. Based on the response elicited to this minimally invasive procedure the patients were divided into the following three groups: A-Responders, B-incomplete responders, C-Non-responders. Surgical intervention was taken up in incomplete responders and Non responders with significant aesthetic and functional compromise. Results: Of all lesions only 16% of the cases responded to non-surgical treatment methods, and were further sub- categorised into: Group A (Responders) which comprised of 2 (8%) of the cases, Group B (Incomplete responders) n= 2(8%) and Group C (Non-Responders) n=21 [84%. All patients belonging to group B and C were treated surgically and fairly good prognosis was documented, as amongst 8% (n=2) + 84% (n=21), 87% (n=20) of the patients were completely cured and re- currence due to the presence of residual tumour was noted in only 13% (n=3) of the cases. Conclusion: As the psychological impact of the congeni- tal deformity on patients is generally more detrimental than it is measurable, except for the post-surgical or traumatic deformities in the treatment of medium size tumours the surgical excision seems to be a worthwhile procedure.","PeriodicalId":151838,"journal":{"name":"Hellenic Archives of Oral & Maxillofacial Surgery","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hellenic Archives of Oral & Maxillofacial Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54936/haoms223155164","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Aim: Infantile hemangiomas are the most common vascular tumours of infancy, affecting up to 12% of infants by the first year of life. The main aim of this study is to present the best treatment modality based on the behaviour of hemangiomas in paediatric population and their pattern of progression or regression with age and in response to intralesional steroids and sclerosing agents administered, along with the rate of recurrence in cases where surgical intervention was done. Materials and methods: A total of 25 patients were in- cluded in this study based on inclusion and exclusion cri- teria. The injections (Kenacort /Kenalog, as intralesional injection) were administered at monthly intervals and patients were reviewed. Based on the response elicited to this minimally invasive procedure the patients were divided into the following three groups: A-Responders, B-incomplete responders, C-Non-responders. Surgical intervention was taken up in incomplete responders and Non responders with significant aesthetic and functional compromise. Results: Of all lesions only 16% of the cases responded to non-surgical treatment methods, and were further sub- categorised into: Group A (Responders) which comprised of 2 (8%) of the cases, Group B (Incomplete responders) n= 2(8%) and Group C (Non-Responders) n=21 [84%. All patients belonging to group B and C were treated surgically and fairly good prognosis was documented, as amongst 8% (n=2) + 84% (n=21), 87% (n=20) of the patients were completely cured and re- currence due to the presence of residual tumour was noted in only 13% (n=3) of the cases. Conclusion: As the psychological impact of the congeni- tal deformity on patients is generally more detrimental than it is measurable, except for the post-surgical or traumatic deformities in the treatment of medium size tumours the surgical excision seems to be a worthwhile procedure.
儿童血管瘤的表现和治疗结果
目的:婴儿血管瘤是婴儿最常见的血管肿瘤,在一岁前影响高达12%的婴儿。本研究的主要目的是根据儿科人群中血管瘤的行为及其随年龄的进展或消退模式,以及对局灶内类固醇和硬化剂的反应,以及手术干预的复发率,提出最佳治疗模式。材料和方法:根据纳入和排除标准,本研究共纳入25例患者。每隔一个月进行一次注射(Kenacort /Kenalog,作为病灶内注射),并对患者进行检查。根据对这种微创手术的反应,将患者分为以下三组:a -反应者,b -不完全反应者,c -无反应者。不完全应答者和无应答者在美学和功能上有明显的妥协,均采用手术干预。结果:在所有病变中,只有16%的病例对非手术治疗方法有反应,并进一步细分为:A组(应答者)2例(8%),B组(不完全应答者)n=2例(8%),C组(无应答者)n=21例(84%)。B组和C组的所有患者均行手术治疗,预后良好,8% (n=2) + 84% (n=21), 87% (n=20)的患者完全治愈,仅13% (n=3)的患者因肿瘤残留而复发。结论:由于先天性畸形对患者的心理影响通常比可测量的更有害,除了手术后或创伤性畸形治疗中等大小的肿瘤外,手术切除似乎是值得的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信