A Clinical Epidemiological Study of Patients with Coronavirus Disease Associated Mucormycosis Treated at A Tertiary Care Nodal Centre

Abstract

Objective: The main objective of this study was to assess clinical and epidemiological factors associated with coronavirus disease associated mucormycosis (CAM) and furthermore to recognize the role of vaccination in preventing the progression of mucormycosis. Materials and methods: A retrospective observational study was conducted on 300 patients with past history of being treat-ed for coronavirus disease and who presented to our department with symptoms of invasive fungal sinusitis. The data were analyzed to assess the factors associated with CAM. Results and Conclusion: Receiving COVID-19 vaccination either one or two doses had some statistically significant associa-tion with CAM, however, only a small number of patients received vaccination doses. Other factors including age, gender, dia-betes (denovo vs. chronic), steroid use, oxygen, and remdesivir administration were not significant. Vaccination may play a key role in lessening the sequelae and mortality due to Covid-19 while providing protection against CAM.