The Role Of Drug-Drink Supervisor by Decreasing The Resitance of Mycobacterium tuberculosis Germs

L. Marlina, Susiwati, Jon Farizal
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Abstract

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. In 2010 WHO Global Report, obtained Indonesian TB data, the total of all TB cases in 2009 were 294,731 cases. TB drug (OAT) is given in the form of a combination of several types namely Isoniazid, Rifampicin, Pyrazinamide & Streptomycin. The emergence of cases of resistance to anti-tuberculosis drugs, especially the occurrence of dual immunity (Multi Drug Resistance = MDR). Factors that cause MDR include patient compliance in drug administration, lack of role of PMO and the phenomenon of "addition syndrome". This study aims to determine the relationship between the role of supervisors taking medication (PMO) and the resistance of the bacteria Mycobacterium tuberculosis in the working area of the Bengkulu city health center. Population and sample of 34 TB patients undergoing treatment therapy in the Bengkulu City Health Center work area. Data were analyzed using the Chi-Square test. The results showed that there was a significant relationship between the role of the supervisor of taking medication (PMO) and the resistance of the bacteria Mycobacterium tuberculosis in the working area of the Bengkulu city health center (p = 0.03 and OR = 6). The study concluded that there was a relationship between the role of the supervisor taking medication (PMO) and the resistance of the bacterium Mycobacterium tuberculosis in the working area of the Bengkulu city health center and the risk of occurrence of 6x. Suggestions for increasing PMO knowledge through counseling and training and giving rewards.
药酒监督员在降低结核分枝杆菌耐药性中的作用
结核病(TB)是一种由结核分枝杆菌引起的传染病。根据2010年世卫组织全球报告获得的印度尼西亚结核病数据,2009年所有结核病病例总数为294,731例。结核病药物(OAT)以几种类型的组合形式给予,即异烟肼、利福平、吡嗪酰胺和链霉素。抗结核药物耐药病例的出现,特别是双重免疫(Multi Drug resistance = MDR)的发生。导致MDR的因素包括患者服药依从性、PMO作用缺失和“附加综合征”现象。本研究旨在确定在Bengkulu市卫生中心工作区域,服药监督员(PMO)的角色与结核分枝杆菌耐药性之间的关系。在Bengkulu市保健中心工作区域接受治疗的34名结核病患者的人口和样本。数据分析采用卡方检验。结果表明,有一个重要的角色之间的关系主管服药(PMO)和细菌的耐药性结核分枝杆菌的工作区域明古鲁市健康中心(p = 0.03, = 6)。这项研究得出的结论是,有一个主管的角色之间的关系(PMO)和服用药物耐药性的结核分枝杆菌的工作区域卫生中心和明古鲁市发生风险6倍。建议通过咨询、培训和奖励来增加PMO知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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