Effect of Assisted Reproductive Technology (ART) on Babies Born: Compared by IVF Laboratories of Two Countries

Linda Wu, Jinzhou Qin, Dikai Zhang, Minqi Zhang, Suzhen Lu, Jennifer Howell, T. Gelety, Bin Wu
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Abstract

Assisted reproductive technology (ART) has been widely used for infertility treatment, but many people have concern about their baby’s health. The objective of this chapter is to provide some detailed data about the effect of ART on human birth babies by analyzing the data from in vitro fertilization (IVF) centers in two countries. All recent records related to a baby’s birth including mother’s age, gestational days, baby’s sex, and birth weight data were collected and analyzed according to fresh or frozen embryo transfer procedure. Normal delivery data without ART were used as control. The result showed that ART patient age is significantly older than non-IVF women; the gestation of fresh and frozen embryo transfer is the same as normal spontaneous conception gestation days, but women pregnant with multiple gestations have shorter gestational period and early birth rate as well as low birth weight; and there is no significant difference in the baby’s weight between ART singleton babies and normal conception babies, but male babies weight is more than female babies, and multiple gestation’s birth weights are significantly lower than singletons, while frozen embryo transfer babies have significantly heavier birth weight than fresh embryo transfer. Also, the frozen embryo transfer technique may significantly decrease premature birth rate. Thus, frozen embryo transfer may be recommended as a health strategy in ART.
辅助生殖技术(ART)对婴儿出生的影响:两国试管婴儿实验室比较
辅助生殖技术(ART)已广泛应用于不孕症的治疗,但许多人对自己孩子的健康感到担忧。本章的目的是通过分析两个国家体外受精(IVF)中心的数据,提供一些关于ART对人类出生婴儿影响的详细数据。根据新鲜或冷冻胚胎移植程序收集和分析所有与婴儿出生有关的近期记录,包括母亲的年龄、妊娠天数、婴儿的性别和出生体重数据。未使用抗逆转录病毒治疗的正常分娩数据作为对照。结果显示,ART患者年龄明显大于非ivf患者;新鲜胚胎移植和冷冻胚胎移植的妊娠期与正常自然受孕的妊娠天数相同,但多胎妊娠的妇女妊娠期较短,早产率低,出生体重低;ART单胎婴儿体重与正常妊娠婴儿体重无显著差异,但男婴体重大于女婴,多胎出生体重明显低于单胎,而冷冻胚胎移植婴儿出生体重明显高于新鲜胚胎移植。此外,冷冻胚胎移植技术可以显著降低早产率。因此,冷冻胚胎移植可能被推荐为抗逆转录病毒治疗的一种健康策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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