PARAOXONASE AND ARYLESTERASE ACTIVITIES IN PREGNANT WOMEN WITH INTAUTERINE GROWTH RESTRICTION: A PRELIMINARY STUDY

Abstract

Objective: To evaluate the role of paraoxonase and arylesterase activities in etiopathogenesis of intrauterine growth restriction Design: Prospective study Setting: Gaziantep Üniversity, Medical School, Department of Obstetrics and Gynecology Patients: Pregnant patient with intrauterine growth restriction. Interventions: Serum analysis and rutin pregnancy interventions. Main outcome measures: Serum paraoxonase and arylesterase activities. Results: We have demonstrated higher paraoxonase and arylesterase activities in patient group. Conclusions: This is the first report about the role of paraoxonase 1, which is a HDL-associated antioxidant enzyme, in etiopathogenesis of intrauterine growth restriction in English literature. Further studies to evaluate the importance of serum paraoxonase and arylesterase activities for prediction of intrauterine growth restriction are needed.