Dissociative Identity Disorder: A Pathophysiological Phenomenon

Abstract

Various hollywood movies have shown a character who switches his personality, one personality does not remember the other at all. In the psychiatric world such a condition is called dissociative identity disorder (DID). The current study shows a collection of some studies showing the pathologic nature of the phenomenon. In this review, we have shown some studies including MRI studies, that demonstrated that the limbic system of DID patients decreases in size (especially hippocampus and amygdala). Moreover, a reduction in the functioning of orbitofrontal cortex is also observed with a reduced cerebral blood in DID patients. In the end, we recommend more studies in the future, to gain more insight about the pathophysiology of this mysterious condition, that will be helpful to treat and manage the patients with DID successfully in the near future.