A Patient Outcome Prediction based on Random Forest

Shan Yang, Xiangwei Zhengy, Feng Yuan
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引用次数: 3

Abstract

Since the research and development value of electronic health records (EHRs) which contains a large number of patient treatment data is very high and meaningful, EHRs has gained attention by researchers in recent years. EHRs has some characteristics such as temporality, sparsity, complexity, irregularity, noisiness and so on, which bring many challenges to direct study the medical data. Thus, an effective feature extraction, or phenotyping from patient EHRs is a key step before any further applications. In this paper, MIMIC-III intensive care database is selected for the experiments. To predict the patient's death outcome (namely death due to illness or still alive), we make full use of the visit records of patients and propose a prediction method that combines the medical concept representation model Med2Vec with random forest algorithm. Experimental results indicate that the proposed method is robust to parameter variations and noise. Besides, compared with other prediction methods, the performance metrics of the proposed method are very well. Finally, the effect of the Med2Vec model is superior to that obtained by raw data (i.e., no feature learning applied to EHRs data).
基于随机森林的患者预后预测
电子病历(electronic health records, EHRs)包含了大量的患者治疗数据,其研发价值非常高且意义重大,近年来受到了研究人员的重视。电子病历具有时效性、稀疏性、复杂性、不规则性、杂讯性等特点,给医疗数据的直接研究带来了诸多挑战。因此,从患者电子病历中提取有效的特征或表型是进一步应用之前的关键步骤。本文选用MIMIC-III重症监护数据库进行实验。为了预测患者的死亡结局(即因病死亡或仍然活着),我们充分利用患者的就诊记录,提出了一种医学概念表示模型Med2Vec与随机森林算法相结合的预测方法。实验结果表明,该方法对参数变化和噪声具有较强的鲁棒性。此外,与其他预测方法相比,该方法的性能指标也很好。最后,Med2Vec模型的效果优于原始数据(即未对EHRs数据进行特征学习)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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