Haemopoietic stem cell transplantation

Abstract

Haemopoietic stem cell transplantation (HSCT) is used to treat a wide variety of haematological and certain solid malignancies, as well as several other serious haematological, immunological, auto-immune and metabolic diseases. This chapter describes the aims and principals of, and indications for, HSCT. The recipient and donor preparation for HSCT, and recipient conditioning treatment including graft-versus-host disease (GvHD) prophylaxis, are outlined. The acute and late complications of HSCT, including GvHD, are described.