Systemic Lupus Erythematous and Vitamin D Deficiency in an Adult Sudanese Patient with Sickle Cell Trait

Abstract

systemic lupus erythematous (SLE) is rarely reported in patients with sickle cell trait, here we reported a case who is known sickle cell trait patient presented with skin rash, palpitation, constipation and recurrent frontal throbbing headache with 2 years’ history of different joints pain, generalized fatigability, hair loss, feeling hot with normal temperature, the patient was found to have positive antinuclear antibody ANA and low level of vitamin D. The vague symptoms made the suspicious of systemic lupus erythematous so difficult, more attention should be given to such association of autoimmune diseases and sickle cell trait not only sickle cell disease.