AMIODARONE INDUCED THYROTOXICOSIS - REVIEW OF TREATMENT

Abstract

Amiodarone is derivative of benzofuran. This medicine was classified as class III anti-arrhythmic drug. Amiodarone is indicated to treat ventricular tachycardia and recurrent ventricular fibrillation. This medicine is a narrow therapeutic index. There are need therapeutic drugs monitoring to minimize adverse drug reaction (ADR). One of ADR of amiodarone therapy is amiodarone induced thyrotoxicosis ( AIT). The review is aimed to determine the therapy of AIT. Review was performed by searching articles published in Pubmed and science direct by typing the keywords of ”therapy" and "amiodaron induced thyrotoxicosis". Prednisone, perchlorate, methimazole and Iopanoic acid (IopAc) are used to treat AIT with various results.