Portulaca oleracea leaves extract attenuates cyclophosphamide toxicity in mice

Abstract

Cyclophosphamide (CTX) is a well-known broad-spectrum anticancer agent however; it has severe side effects on vital organs. Portulaca oleracea that belongs to family Portulacaceae showed promising nutritional and biomedical properties. This research aimed to estimate the effect of P. oleracea leaves extract (POLE) on CTX toxicity in male CD-1 mice. Total phenolic, flavonoids contents, total antioxidant capacity (TAC)