{"title":"[Significance of the alveolo-arterial PO2 gradient in the diagnosis of pulmonary thromboembolism].","authors":"N Mojsoski, N Kosanović, M Stikovac","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The diagnostic value of alveolar-arterial PO2 gradient P(A-a)O2 in pulmonary thromboembolism is tested. The significance of alveolar-arterial PO2 gradient in acute pulmonary thromboembolism was determined in prospective study. The study group consisted of 7 patients with pulmonary thromboembolism documented by digital-subtraction angiography (DSA) and lung scans and ten healthy subjects with normal alveolar-arterial PO2 gradient. Hypoxemia was present in 3 patients, hypocapnia in 4 patients and an increased P(A-a)O2 gradient in all 7 patients. The results suggest that a normal P(A-a)O2 gradient in patients during room air breathing can be used as evidence against the presence of pulmonary emboli. P(A-a)O2 gradient is a very sensitive diagnostic parameter in acute pulmonary embolism but procedure is fast.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"43 1-2","pages":"113-5"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The diagnostic value of alveolar-arterial PO2 gradient P(A-a)O2 in pulmonary thromboembolism is tested. The significance of alveolar-arterial PO2 gradient in acute pulmonary thromboembolism was determined in prospective study. The study group consisted of 7 patients with pulmonary thromboembolism documented by digital-subtraction angiography (DSA) and lung scans and ten healthy subjects with normal alveolar-arterial PO2 gradient. Hypoxemia was present in 3 patients, hypocapnia in 4 patients and an increased P(A-a)O2 gradient in all 7 patients. The results suggest that a normal P(A-a)O2 gradient in patients during room air breathing can be used as evidence against the presence of pulmonary emboli. P(A-a)O2 gradient is a very sensitive diagnostic parameter in acute pulmonary embolism but procedure is fast.
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