The simulation of acoustic field in the design of ultrasound driving device for site nano-drug delivery

Abstract

Particle manipulation plays a very important role in many fields, such as ultrasound drug delivery, cell manipulation and trapping molecules. Ultrasonic manipulation, which uses acoustic radiation forces, is a contactless manipulation technique. When the particles suspended in a fluid, the ultrasound radiation forces made the particles concentrate in a designated location. Here it is reported on a simulation for two-dimensional arraying based on the superposition of two in-plane orthogonally oriented standing pressure waves. First, we do the simulation of one-dimensional acoustic field with the FEA software of ANSYS. Then, we got the two-dimensional acoustic field by modify the PZT model. We make the particles concentration when the model was excited with a 14 V amplitude signal at 1.5 MHz.