Complicated Gestational Diabetes: A Challenge!

Rutul Gokalani, Vandana Amin, B. Saboo, M. Saiyed
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Abstract

Abstract Gestational diabetes is a condition caused by insulin resistance and multiple metabolic abnormalities; the prevalence of gestatinal diabetes mellitus (GDM) has been rising and has almost become parallel to obesity and type 2 diabetes. However, the mechanism and treatment points are still debatable. Hyperglycemia in pregnancy (HIP) is social instability as woman infertility is associated with it. If timely screened and achieved targeted glycemic control, it gives the desired outcome of pregnancy especially in pregestational diabetes. Support of family and thorough understanding of the disease is crucial in such situations as it requires multidisciplinary management, for example, structured self monitoring blood glucose (SMBG), diet and nutrition, multiple daily insulin injections with dose adjustment, avoiding hypoglycemia, and mental stability. Hyperglycemia in pregnancy (HIP) as a whole (pregestational and gestational diabetes) is one of the leading causes of woman infertility, miscarriages, abortions, fetal complications and anomalies3 Diabetes in pregnancy is challenging task for health care professionals, as the opinion on diagnosis differ and the treatment options are limited. Main stream of treatment roam around insulin with lifestyle modification and metformin4 5 (a dilemma for the doctors). It requires more attention and discipline than usual, as it involves two lives and more emotions attached to it. Apart from health, women have to face social instability (e.g., lack of family support, family conflict, violence, and blaming a woman), once detected with GDM, making them feel isolated and unlucky for the family. This poor attitude leads to worsening mental health in the females who are already exposed to anxiety and depression. In addition, gestational diabetes is an economic burned to the common earning man, as the overall cost of the disease is high. In this case, in spite of investing a huge amount of money, the woman has to undergo multiple traumas. Therefore, management of such cases is crucial. One such case is of a 34-year-old woman detected with typical symptoms of type II diabetes since 6.5 years. She was on oral hypoglycemic agents (OHAs) for a long time. Her grandfather and father had a history of type II diabetes. At the time of diagnosis, her HbA1c was 10.8% without ketosis. She belongs to Chanasma, a rural area in Mehsana district in North Gujarat. She is well educated and working as an officer (Patwari) in the government sector. After tying a knot at the age of 23 years, she had history of multiple abortions (7 reported) culprit being hyperglycemia. In year 2017, on her 7th gestational week she was referred to Arogyam Health Care—Diabetes Clinic.
复杂的妊娠糖尿病:一个挑战!
妊娠期糖尿病是由胰岛素抵抗和多种代谢异常引起的疾病;妊娠期糖尿病(GDM)的发病率一直在上升,几乎与肥胖和2型糖尿病并肩。然而,其机制和治疗要点仍有争议。妊娠期高血糖症(HIP)是一种社会不稳定因素,与女性不孕有关。如果及时筛查并达到有针对性的血糖控制,它可以获得妊娠的预期结果,特别是在妊娠糖尿病中。在这种情况下,家庭的支持和对疾病的全面了解至关重要,因为它需要多学科管理,例如,有组织的自我监测血糖(SMBG)、饮食和营养、每日多次胰岛素注射并调整剂量、避免低血糖和精神稳定。妊娠期高血糖症(HIP)作为一个整体(妊娠期和妊娠期糖尿病)是妇女不孕、流产、流产、胎儿并发症和异常的主要原因之一。妊娠期糖尿病是卫生保健专业人员面临的一项具有挑战性的任务,因为诊断意见不一,治疗方案有限。主流的治疗围绕着胰岛素和生活方式的改变以及二甲双胍(这对医生来说是个难题)。它需要比平时更多的关注和纪律,因为它涉及到两个生命和更多的情感。除了健康之外,妇女一旦被发现患有GDM,就必须面对社会不稳定(例如,缺乏家庭支持、家庭冲突、暴力和责备妇女),使她们感到孤立,对家庭不利。这种不良的态度导致已经暴露在焦虑和抑郁中的女性的心理健康恶化。此外,妊娠期糖尿病对普通收入男性来说是一项经济损失,因为该疾病的总体成本很高。在这种情况下,尽管投入了巨额资金,但该女子不得不承受多重创伤。因此,对此类病例的管理至关重要。其中一例是一名34岁的妇女,自6.5年以来被发现有典型的II型糖尿病症状。她长期服用口服降糖药(OHAs)。她的祖父和父亲都有II型糖尿病病史。诊断时,HbA1c为10.8%,无酮症。她来自古吉拉特邦北部梅哈萨纳地区的农村地区查纳斯马。她受过良好的教育,在政府部门担任官员(Patwari)。23岁结婚后,有多次流产史(7例),罪魁祸首是高血糖。2017年,在她怀孕第7周时,她被转介到Arogyam保健糖尿病诊所。
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