FEM modeling to evaluate the effect of plaque formation over the temperature and blood flow

D. Avila-Cabrera, J. Gutiérrez-Martínez, L. Leija-Salas, A. Vera-Hernández, M. I. Gutiérrez- Velazco, C. Trujillo-Romero
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Abstract

The global prevalence of peripheral arterial disease (PAD) is 3-10%, which can increase to 15-20% from the age of 70 and has an annual mortality of 4-6%. This disease can trigger more serious problems, such as poor circulation, diabetic foot, amputations.The objective is to understand the relationship between the generation of plaque inside the arteries with variations in blood flow and its temperature, creating a computational simulation based on the finite element method, for which the flow pressure, the flow velocity and heat transfer to nearby tissues, taking the size of the radius of the artery as a multiparametric variable.The change in the size of the arterial radius patient simulates a healthy one if the artery is wide and the reduction of the arterial radius simulates a patient with plaque formation.The results obtained with these simulations show that the velocity decreases when the arterial radius is reduced, which simulates a patient with blood problems, on the other hand, the flow pressure decreases if the patient is healthy. The temperature analysis gives us information about the behavior of the tissues, a decrease in temperature could indicate that there is ischemia or some disease.
用有限元模型评估斑块形成对温度和血流的影响
外周动脉疾病(PAD)的全球患病率为3-10%,从70岁起可增加到15-20%,年死亡率为4-6%。这种疾病会引发更严重的问题,比如血液循环不良、糖尿病足、截肢。目的是了解动脉内斑块的产生与血流变化及其温度之间的关系,以动脉半径大小为多参数变量,以血流压力、流速和向附近组织的热量传递为基础,建立基于有限元方法的计算模拟。如果动脉较宽,则动脉半径的变化与健康患者相似,而动脉半径的减小与斑块形成患者相似。模拟结果表明,当动脉半径减小时流速减小,模拟的是有血液问题的病人,反之,如果病人是健康的,血流压力减小。温度分析为我们提供了有关组织行为的信息,温度下降可能表明存在缺血或某些疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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