Temperature response analysis based on pulse width irradiation of 2.45 GHz microwave hyperthermia

Abstract

This paper describes the temperature response analysis due to the heat effect as a result of microwave hyperthermia irradiation in biological medium for a finite duration time. Since we use the on and off irradiation method, realized by pulse width signal with certain duty cycle value, it is important to know whether the on heating duration can generate sufficient desired heat and the off duration decrease significantly. The bioheat transfer equation and its approximation can help us in analyzing the above relation. According to the analysis and real experiment, our proposed pulse width irradiation with 10s pulse period and its duty cycle variation values used in our 2.45 GHz microwave hyperthermia system can provide sufficient temperature increase during on duration and not significant decrease temperature during off duration, to get the required hyperthermia temperature response.