Do We Need to Repeat the Initially Normal Head Computerized Tomography for Patients with Mild Head Trauma Using Anticoagulant and/or Antiplatelet Therapy?

Yaşar Çatal, M. Günalp, S. Genç, Ahmet Burak Oğuz, A. Koca, Onur Polat
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Abstract

Objective: Patients using anticoagulant and/or antiplatelet (AC/AP) medications are at an increased risk of intracranial hemorrhage (ICH) subsequent to head trauma and current guidelines recommend a head computed tomography (CT) scan for these patients. There is a lack of consensus about management recommendations for mild head trauma patients on AC/AP treatment who had an initially normal head CT. The aim of this study was to determine the rate of delayed ICH after a 24-hour observation in patients with mild head trauma using AC/AP who had an initially normal head CT. Method: Patients aged 18 and older, using AC/AP drugs with mild head trauma were included prospectively. Patients underwent head CT for suspected bleeding. A repeat CT scan was performed after a 24-hours observation period for the patients who had an initially normal head CT for detecting delayed intracranial hemorrhage. Result: A total of 101 patients were included and, 57.4% (n=58) of the patients were female. Delayed ICH was detected in 2.9% (n=3) of the patients after a 24-hour observation. None of the patients with delayed ICH needed surgical treatment or further intervention. Delayed ICH was found in patients who used acetylsalicylic acid (n=1), dabigatran (n=1), and apixaban (n=1). Conclusion: In patients with mild head trauma using AC/AP, delayed intracranial hemorrhage is rare and may be clinically insignificant. A repeat CT scanning after 24-hour observation may not be necessary for patients with mild head trauma using AC/AP therapy who had initially normal head CT.
对于使用抗凝和/或抗血小板治疗的轻度头部创伤患者,我们是否需要重复最初正常的头部计算机断层扫描?
目的:使用抗凝和/或抗血小板(AC/AP)药物的患者在头部外伤后颅内出血(ICH)的风险增加,目前的指南建议对这些患者进行头部计算机断层扫描(CT)扫描。对于最初头部CT正常的轻度颅脑外伤患者进行AC/AP治疗的管理建议缺乏共识。本研究的目的是在使用AC/AP对轻度头部外伤患者进行24小时观察后确定延迟性脑出血的发生率,这些患者最初的头部CT正常。方法:前瞻性纳入18岁及以上使用AC/AP药物的轻度颅脑外伤患者。疑似出血患者行头部CT检查。对于最初头部CT正常的患者,在24小时观察期后进行重复CT扫描,以检测延迟性颅内出血。结果:共纳入101例患者,女性占57.4% (n=58)。24小时观察后,迟发性脑出血发生率为2.9% (n=3)。迟发性脑出血患者均无需手术治疗或进一步干预。迟发性脑出血见于使用乙酰水杨酸(n=1)、达比加群(n=1)和阿哌沙班(n=1)的患者。结论:在使用AC/AP治疗轻度颅脑外伤的患者中,迟发性颅内出血是罕见的,可能在临床上不显著。对于使用AC/AP治疗的轻度颅脑损伤患者,最初头部CT正常,24小时观察后可能不需要重复CT扫描。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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