{"title":"Effect of Streptozocin on the Langerhans Islands in the pancreas of\nbirds","authors":"Sarah Jassim Abd, Satar Abood Faris","doi":"10.21931/rb/css/2023.08.01.89","DOIUrl":null,"url":null,"abstract":"In the current study, birds (Columba livia ) were used as a new model\nto study the effect of streptozotocin on the pancreas gland and the blood glucose\nlevel. Three concentrations of 75,65,55 mg/kg were adopted for five consecutive\ndays with one IP dose daily. The experimental animals showed a gradual rise in\nblood glucose the average glucose in the first week of the experiment was usual\nfor the three groups compared with the control group, while there was a significant change in the blood glucose level in the three groups at the end of the experiment (4th week), where the average glucose in the streptozotocin groups was 55\nmg/kg (213.80 ± 12.43) mg/dl and the group 65 mg/kg(282.60 ± 16.78) mg/dl\nand a group of 75 mg/kg( 371.0 ± 38.39) mg/dl.\nKeywords: Streptozocin, Langerhans islands, pancreas.","PeriodicalId":443152,"journal":{"name":"Sumer 1","volume":"5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sumer 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21931/rb/css/2023.08.01.89","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In the current study, birds (Columba livia ) were used as a new model
to study the effect of streptozotocin on the pancreas gland and the blood glucose
level. Three concentrations of 75,65,55 mg/kg were adopted for five consecutive
days with one IP dose daily. The experimental animals showed a gradual rise in
blood glucose the average glucose in the first week of the experiment was usual
for the three groups compared with the control group, while there was a significant change in the blood glucose level in the three groups at the end of the experiment (4th week), where the average glucose in the streptozotocin groups was 55
mg/kg (213.80 ± 12.43) mg/dl and the group 65 mg/kg(282.60 ± 16.78) mg/dl
and a group of 75 mg/kg( 371.0 ± 38.39) mg/dl.
Keywords: Streptozocin, Langerhans islands, pancreas.