Effect of Streptozocin on the Langerhans Islands in the pancreas of birds

Sarah Jassim Abd, Satar Abood Faris
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Abstract

In the current study, birds (Columba livia ) were used as a new model to study the effect of streptozotocin on the pancreas gland and the blood glucose level. Three concentrations of 75,65,55 mg/kg were adopted for five consecutive days with one IP dose daily. The experimental animals showed a gradual rise in blood glucose the average glucose in the first week of the experiment was usual for the three groups compared with the control group, while there was a significant change in the blood glucose level in the three groups at the end of the experiment (4th week), where the average glucose in the streptozotocin groups was 55 mg/kg (213.80 ± 12.43) mg/dl and the group 65 mg/kg(282.60 ± 16.78) mg/dl and a group of 75 mg/kg( 371.0 ± 38.39) mg/dl. Keywords: Streptozocin, Langerhans islands, pancreas.
链脲佐菌素对鸟类胰腺朗格汉斯岛的影响
本研究以鸟类(Columba livia)为新模型,研究链脲佐菌素对胰腺和血糖水平的影响。采用75、65、55 mg/kg 3种浓度,连续5天,每天1次IP剂量。实验动物显示逐步增加inblood葡萄糖平均葡萄糖在第一周的实验usualfor三组与对照组相比,虽然有一个显著的变化在血糖水平在三组实验结束时(4周),平均葡萄糖链脲霉素组55毫克/公斤(213.80±12.43)mg / dl和65毫克/公斤(282.60±16.78)毫克/ dland一群75毫克/公斤(371.0±38.39)mg / dl。关键词:链脲菌素;朗格汉斯岛;胰腺;
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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