Sinus bradycardia as a phenotype in opioid dependence syndrome, acute withdrawal state, a rare case series

Abstract

Tachycardia is one of the most common physiological phenomena in Opioid withdrawal and is due to the state of transient catecholamine surge. However, till date, no studies have reported bradycardia during opioid withdrawal (acute phase). Hereby, we intend to report rare cases of two young males who developed sinus bradycardia in opioid withdrawal (acute phase). Close electro-clinical monitoring of bradycardia for possible prevention of mortality in opioid withdrawal is proposed.