Stem Cell Therapies for Cardiac Disease: Which Cell Types Are the Best

Ji Wen
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Abstract

Stem cell therapy for the treatment of cardiovascular disease is increasingly being researched during the past few decades. Due to the risk of cardiac transplantation surgery and the nature of cardiac cell lines, the regenerative potential of stem cell therapy is being extremely expected. Popular cell lines are discussed in this study, which includes mesenchymal stem cells, bone marrow-derived mononuclear stem cells, embryonic stem cells, hematopoietic stem cells, endothelial progenitor cells, tissue-specific stem cells, umbilical cord blood stem cells, skeletal myoblast and induced pluripotent stem cells. The purpose of this study is to review the current use of various cell types for stem cell therapy in cardiovascular patients, as mentioned above. Additionally, optimal delivery methods of stem cell therapies are also discussed in patients with and without secondary stroke conditions. Literature from the Internet was searched and primary studies with the cell types of interest were carefully examined and included in the study. Although from current literature in the field stem cell therapies have great potential to be used in cardiovascular patients, more extensive research with a greater number is warranted before widespread application in the clinical setting.
干细胞治疗心脏病:哪种细胞类型是最好的
在过去的几十年里,干细胞治疗心血管疾病的研究越来越多。由于心脏移植手术的风险和心脏细胞系的性质,干细胞治疗的再生潜力备受期待。本研究讨论了常用的细胞系,包括间充质干细胞、骨髓来源的单个核干细胞、胚胎干细胞、造血干细胞、内皮祖细胞、组织特异性干细胞、脐带血干细胞、成骨骼肌细胞和诱导多能干细胞。如上所述,本研究的目的是回顾目前在心血管患者干细胞治疗中使用的各种细胞类型。此外,干细胞治疗的最佳递送方法也讨论了患者的继发性卒中条件。从互联网上检索文献,并仔细检查了感兴趣的细胞类型的初步研究,并将其纳入研究。虽然从目前的文献来看,干细胞疗法在心血管患者中具有巨大的应用潜力,但在临床广泛应用之前,需要进行更广泛的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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