Simulation of oxygen supply in the tissue and its relationship with Lung Qi-Deficiency

Abstract

Based on the respiratory and circulatory system, a dynamic model describing oxygen metabolism in human body was set up. The effect on oxygen pressure in the tissue due to the change of the parameters was revealed through numerical analysis to the parametric equation of the model. Two treating methods to raise oxygen pressure in the tissue were worked out, which accorded with the results of clinical observations. The results of such model showed that the abnormality of the circulatory and respiratory parameters always lead to a reduction of PO2 (O2 pressure) in tissue fluid, and then a Lung Qi-Deficiency Syndrome (QDS). This article also discuss the quantitative relationship between the changes of the parameters of the heart-lung system and the oxygen pressure in the tissue, then provide index to evaluate clinical treatment and analyze the body's oxygen metabolism, which is great significant for the precaution and treatment of low oxygen environment.