{"title":"Haematological drugs","authors":"C. Waldmann, A. Rhodes, N. Soni, J. Handy","doi":"10.1093/med/9780198723561.003.0015","DOIUrl":null,"url":null,"abstract":"This chapter discusses haematological drugs and includes discussion on anticoagulants and heparin-induced thrombocytopenia (including unfractionated heparin, low-molecular weight heparins, danaparoid, coumarins, synthetic pentasaccharides, the direct oral anticoagulants, and thromboprophylaxis in critical care patients), thrombolysis (definition of thrombolysis, physiology of fibrinolysis, contraindications to thrombolysis, factors influencing a successful outcome, myocardial infarction, acute limb ischaemia, and pulmonary embolism), and antifibrinolytics (describing the efficacy of tranexamic acid in reducing traumatic bleeding, the efficacy of tranexamic acid in reducing surgical bleeding, and the efficacy of tranexamic acid in postpartum haemorrhage).","PeriodicalId":406870,"journal":{"name":"Oxford Desk Reference: Critical Care","volume":"1 1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Desk Reference: Critical Care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/med/9780198723561.003.0015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This chapter discusses haematological drugs and includes discussion on anticoagulants and heparin-induced thrombocytopenia (including unfractionated heparin, low-molecular weight heparins, danaparoid, coumarins, synthetic pentasaccharides, the direct oral anticoagulants, and thromboprophylaxis in critical care patients), thrombolysis (definition of thrombolysis, physiology of fibrinolysis, contraindications to thrombolysis, factors influencing a successful outcome, myocardial infarction, acute limb ischaemia, and pulmonary embolism), and antifibrinolytics (describing the efficacy of tranexamic acid in reducing traumatic bleeding, the efficacy of tranexamic acid in reducing surgical bleeding, and the efficacy of tranexamic acid in postpartum haemorrhage).