Using warm compresses to reduce IL-1β levels in dysmenorrhea: An evaluation of quasy experimental study

Abstract

Primary dysmenorrhoea is a gynochological problems that occured among adolescents and women of reproductive age. In primary dysmenorrhea an increase of pro-inflammatory cytokine IL-1β levels. The aim of this study was determine the effect of warm compresses to reduce IL-1β levels in primary dysmenorrhoea. Research desaign used quasy experiment with pretest-posttest control group design and post test only control group design. The population of this study were all students of Health Science Faculty of Unipdu Jombang who experienced dysmenorrhoea, with a total sample of 24 respondents taken by using simple random sampling techniques and met inclusion and exclusion criteria. Hot water bag were the equiptments of this study. The instrument for measuring pain used NRS (Numeric Rating Scale), IL-1 β levels used the ELISA method. The data analyzed by using Wilcoxon test and Mann-Whitney Test with α ≤ 0.05. The results of study showed there was an effect of warm compresses on dysmenorrhea with a significant value (ρ) of 0.000 (p ≤ 0.05). There were significant differences of the intensity of menstrual pain and IL-1β levels between warm compress group vs. control group (p≤0.05). Warm compresses are effectively to reduce IL-1β levels on primary dysmenorrhea, it can be used as an alternative intervention to overcome complaints of primary dysmenorrhea.