Photodermatit developed with pirfenidone treatment in patient diagnosed with IPF

Ezgi Akkuş, Deniz Çelik, Özkan Yetkin, Hüseyin Lakadamyalı
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Abstract

Idiopathic pulmonary fibrosis (IPF) is the most common of the major idiopathic interstitial pneumonia (IIP) of unknown etiology, often presenting in advanced age, limited to the lungs, characterized by histopathologically and/or radiologically usual interstitial pneumonia (UIP) pattern, and progressing with chronic, progressive fibrosis. is the most common form. Since IPF is a disease with irreversible fibrosis, there is no curative treatment except lung transplantation. The aim of the treatments given is to stop the progression of the disease, to prevent exacerbations and to prolong the survival time. The greatest improvement in the treatment of IPF in recent years has been the use of antifibrotic drugs (Pirfenidone and nintedanib) that prevent fibrosis developing in the lung parenchyma. In this case, we aimed to present the side effect of photodermatitis in a patient who applied to our outpatient clinic with complaints of shortness of breath and cough for many years and was diagnosed with IPF and started on pirfenidone treatment.
诊断为IPF的患者在吡非尼酮治疗后出现光性皮炎
特发性肺纤维化(IPF)是主要特发性间质性肺炎(IIP)中最常见的一种,其病因不明,通常表现为高龄,局限于肺部,以组织病理学和/或影像学上常见的间质性肺炎(UIP)为特征,并以慢性进行性纤维化为进展。是最常见的形式。由于IPF是一种具有不可逆性纤维化的疾病,除了肺移植之外没有治愈的治疗方法。所给予治疗的目的是阻止疾病的进展,防止恶化和延长生存时间。近年来,IPF治疗的最大进步是使用抗纤维化药物(吡非尼酮和尼达尼布),防止肺实质纤维化的发展。在本病例中,我们的目的是介绍一位以呼吸短促和咳嗽为主诉多年来到我们门诊就诊的患者的光性皮炎的副作用,该患者被诊断为IPF,并开始使用吡非尼酮治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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