Correlates of abnormal hysteroscopy findings among infertile women in Nigeria

J. Ugboaja, Charlotte Oguejiofor Blanche, E. Oranu, E. N. Monago, O. Ogelle, A. Igwegbe
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Abstract

This study aimed to evaluate the correlates of abnormal hysteroscopy among infertile women seen in 2 new Fertility/ Gynaecological Endoscopy units in Nigeria. Data was collected on biosocial and clinical characteristics of the patients as well as the findings at hysteroscopy and was analyzed with STATA software, version 12.0 SE (Stata Corporation, TX, USA) for the correlates of abnormal hysteroscopy using the Pearson’s chi square test. P- value of less than 0.05  at a confidence interval of 95% was taken as significant. One hundred and twelve (70.4%) out of 159 women had abnormal findings at hysteroscopy. The mean age of the women was 36.6 ± 6.2 years. The uterine lesions found on hysteroscopy were mainly intrauterine adhesions (47.8%), endometrial polyps (17.6%), submucous fibroids (11.9%) and mullerian duct abnormalities (10.7%). Abnormal hysteroscopy was significantly associated with secondary infertility (X2=5.4; p=0.02), duration of infertility more than 2 years (X2=16.5; p<0.001), menstrual abnormalities (X2=4.6; p=0.03), secondary dysmenorrhea (X2=4.9; p=0.03) and abnormal hysterosalpingogram findings (X2=5.0; p=0.03). There was no significant relationship of abnormal hysteroscopy with pelvic ultrasound findings (X2=1.82; p=0.18). Abnormal hysteroscopy was significantly associated with secondary infertility, menstrual abnormalities, secondary dysmenorrhea and abnormal HSG findings. Therefore, diagnostic hysteroscopy is strongly recommended in these classes of women.   Key word:  Clinical, correlates, abnormal hysteroscopy, infertile women, Nigeria, Nnewi.
尼日利亚不孕妇女宫腔镜检查结果异常的相关性
本研究旨在评估尼日利亚2个新的生育/妇科内窥镜检查单位中不孕妇女宫腔镜检查异常的相关性。收集患者的生物社会和临床特征以及宫腔镜检查结果的数据,并使用STATA软件,版本12.0 SE (STATA Corporation, TX, USA)使用Pearson卡方检验分析宫腔镜异常的相关因素。P值在95%置信区间内小于0.05为显著性。159例女性中有112例(70.4%)在宫腔镜检查中发现异常。女性平均年龄36.6±6.2岁。宫腔镜检查发现的子宫病变主要为宫内粘连(47.8%)、子宫内膜息肉(17.6%)、黏膜下肌瘤(11.9%)和苗勒管异常(10.7%)。宫腔镜异常与继发性不孕症显著相关(X2=5.4;p=0.02),不孕症持续时间大于2年(X2=16.5;p<0.001),月经异常(X2=4.6;p=0.03),继发性痛经(X2=4.9;p=0.03),子宫输卵管造影异常(X2=5.0;p = 0.03)。宫腔镜检查异常与盆腔超声检查结果无显著相关性(X2=1.82;p = 0.18)。宫腔镜检查异常与继发性不孕症、月经异常、继发性痛经和异常的HSG结果显著相关。因此,强烈建议在这类妇女中进行诊断性宫腔镜检查。关键词:临床,相关因素,宫腔镜异常,不孕妇女,尼日利亚,奈威。
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