Efekti antibakteror i Thymus serpyllum ndaj E. faecalis në dentinën radikulare

Ariana Kameri
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Abstract

Despite the advanced use of preparation techniques, in- struments, application of irrigants, namely simultaneous root canal medications, endodontic failures can occur. Therefore, in order to find a new alternative, we have de- termined that the purpose of this in vitro research is: to evaluate the antibacterial efficiency of the extract of Thy- mus serpyllum alone and in combination with NaOCl 2%, as well as Chlorhexidine against Enterococcus faecalis in the solution with dentin powder using the agar disk diffusion method. The zones of inhibition caused by the herbal ex- tract of Thymus serpyllum were evaluated after 5 minutes, 60 minutes and 24 hours, and were compared with the standard solutions of NaOCl 2 % and Chlorhexidine after mixing with the dentin powder. The statistical analysis of the results was done with One Way ANOVA and the Kruskal Wallis test. Sodium hypochlorite 2% has shown antibacte- rial effect against Enterococcus faecalis by forming a wide zone of inhibition, but after mixing with dentin powder, its effect is reduced. Chlorhexidine 2% has shown an antibac- terial effect against E.faecalis, giving an inhibition zone, which is reduced under the influence of dentin powder. Chlorhexidine after mixing with plant extracts of Thymus serpyllum has resulted in more powerful antibacterial effect against E.faecalis. The herbal extract of Thymus serpyllum has been shown to be effective against E.faecalis, which is re- duced under the influence of dentin powder.
尽管使用了先进的预备技术、器械、冲洗剂的应用,即同时使用根管药物,但仍可能发生根管失败。因此,为了寻找一种新的替代方法,我们确定了本次体外研究的目的是:用琼脂盘扩散法,评价蛇毛菌提取物单独使用和与2% NaOCl、氯己定联合使用对牙本质粉溶液中粪肠球菌的抑菌效果。分别测定了百里草提取物在5分钟、60分钟和24小时后的抑菌带,并与2% NaOCl和氯己定标准溶液与牙本质粉混合后的抑菌带进行了比较。统计分析采用单因素方差分析和Kruskal Wallis检验。2%次氯酸钠对粪肠球菌有较宽的抑菌区,但与牙本质粉混合后抑菌效果降低。2%氯己定对粪肠球菌有一定的抑菌作用,在牙本质粉的作用下抑菌作用减弱。氯己定与丝绒胸腺植物提取物混合后对粪肠杆菌的抑菌效果更强。研究表明,麝香草提取物对粪肠球菌有一定的抑制作用,但在牙本质粉的作用下粪肠球菌的抑制作用降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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