Diagnostic Efficacy of the Carba NP Strip Test for Carbapenemase Detection ‎

Abstract

OXA-48 gene. Pseudomonas isolates were positive for the bla VIM gene as a single gene. The Carba NP strip method exhibited high sensitivity and specificity, but the tube method had a higher diagnostic performance in Pseudomonas isolates. Conclusion: The current study highlights that Carba NP strip test can be a reliable and excellent alternative to other tedious and expensive standard techniques, making carbapenem resistance diagnosis reachable to routine laboratories. The Carba NP strip test is simple, inexpensive, and rapid. It can be implemented in low-resource healthcare settings for early detection of carbapenem resistance, hence initiating proper therapy. Further studies on broad scales are recommended to study the effect of other carbapenemase genes on sensitivity and specificity.