CASUISTIC CASE OF RETROPHARYNGEAL ABSCESS WITH AN ATYPICAL CLINICAL PICTURE IN A CHILD

O. Plaksivy, O. Mazur, M. Tsurkan, T. Chyfurko, K. Yakovets
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Abstract

Retropharyngeal abscess is an acute purulent inflammation of the lymph nodes and loose tissue of the pharyngeal space. The pharyngeal space spans from the base of the skull to the lower edge of the pharynx. It is bounded anteriorly by the posterior pharyngeal wall and posteriorly by the prevertebral fascia. Laterally, it is bounded by the parapharyngeal spaces and the neurovasc ular bundles of the neck, and it extends into the posterior mediastinum inferiorly., which facilitates the spread of abscess into the mediastinum, causing mediastinitis. The lymph nodes of the pharyngeal space are regional to the nasopharynx, oropharynx, posterior nasal cavity, auditory tube, and tympanic cavity. Therefore, the causative factors of retropharyngeal abscess are inflammatory diseases of the upper respiratory tract and middle ear. Retropharyngeal abscess is an extremely serious pathology of early childhood and is observed in children of the first 4 years of life. In children over the age of 4, it practically does not occur due to regression and obliteration of the lymph nodes and regression of the pharyngeal space.We have described a clinical case of the retropharyngeal abscess in a child aged 4 years and 10 months, the symptoms and course of which are radically different from the classic symptoms of this pathological condition in children of early childhood. In the differential diagnosis of the retropharyngealt abscess it is necessary to distinguish it from a number of diseases, namely ARVI, acute nasopharyngitis, tonsillitis, including lingual and pharyngeal tonsils, stomatitis, paratonsillitis, paratonsillar abscess, Ludwig's angina, parapharyngeal phlegmon, phlegmon of the neck, mononucleosis, acute stenosing laryngotracheitis, acute subglottic laryngitis (pseudocroup), pneumonia,cervical lordosis, aneurysm of ascending aorta or cervical artery, tumors of the nasopharynx, foreign bodies of pharynx, larynx, and cervical esophagus.Complications make this disease extremely dangerous. The most common complications are observed in the second week of the disease in cases of undiagnosed process, namely laryngeal oedema with development of acute stenosis, pneumonia, sepsis, meningoencephalitis, spread of inflammation to the interfascial space of the neck and posterior mediastinum with development of purulent mediastinitis and varrious septic complications.The most unexpected and dangerous complication is death by asphyxia, which occurs when the abscess opens spontaneously due to aspiration of pus.Thus, retropharyngeal abscess occurs mainly in early childhood due to the peculiarities of the anatomical structure of the pharyngeal space, loose tissue and lymph nodes. These anatomical features of the pharynx and pharyngeal space in childhood and the causative factors should be taken into account by the doctor in case of any deterioration of the child's general condition accompanied by hyperthermia, impaired breathing and swallowing difficulties. However, the less frequent but possible occurrence of a retropharyngeal abscess with atypical clinical symptoms after the age of 4 years should not be forgotten.The Commission on Biomedical Ethics of the BSMU of the Ministry of Health of Ukraine (Chernivtsi) determined that the study was conducted in compliance with the "Rules of Ethical Principles for Scientific Medical Research Involving Human Subjects" approved by the Declaration of Helsinki (1964-2013), ICH GCP (1996), Regulation (EU) No. 609 of 24 November 1986, and Orders of the Ministry of Health of Ukraine No. 690 of 23 September 2009, No. 944 of 14 December 2009, No. 616 of 03 August 2012. The material presented in this article may be recommended for publication (Protocol No. 7 of 18 May 23).
儿童咽后脓肿的不典型临床表现
咽后脓肿是一种急性化脓性炎症的淋巴结和松散组织的咽间隙。咽间隙从颅底延伸到咽的下缘。它的前面是咽后壁,后面是椎前筋膜。在侧面,它被咽旁间隙和颈部的神经血管束所包围,并向下延伸至后纵隔。,从而促进脓肿向纵隔扩散,引起纵隔炎。咽间隙淋巴结分布于鼻咽部、口咽部、后鼻腔、听管和鼓室。因此,咽后脓肿的病因是上呼吸道和中耳的炎症性疾病。咽后脓肿是一种非常严重的儿童早期病理,并观察到在儿童的头4年的生活。在4岁以上的儿童中,由于淋巴结的消退和闭塞以及咽间隙的消退,实际上不会发生这种情况。我们描述了一个4岁零10个月的儿童咽后脓肿的临床病例,其症状和病程与早期儿童咽后脓肿的典型症状完全不同。在咽后脓肿的鉴别诊断中,有必要将其与多种疾病区分,即急性呼吸道感染、急性鼻咽炎、扁桃体炎(包括舌和咽扁桃体)、口炎、副扁桃体炎、副扁桃体脓肿、路德维希心痛、咽旁痰、颈部痰、单核细胞增多症、急性狭窄性喉气管炎、急性声门下喉炎(假性)、肺炎、颈椎前凸、升主动脉或颈动脉动脉瘤、鼻咽肿瘤,咽、喉、颈食管异物。并发症使这种疾病极其危险。最常见的并发症发生在发病后第二周,即喉部水肿并发急性狭窄、肺炎、脓毒症、脑膜脑炎、炎症扩散至颈部筋膜间隙和后纵隔并发化脓性纵隔炎和各种脓毒性并发症。最意想不到和最危险的并发症是窒息死亡,这发生在脓肿因吸脓而自发打开时。因此,咽后脓肿主要发生在儿童早期,这是由于咽间隙解剖结构的特殊性、组织疏松和淋巴结。当儿童的一般情况恶化并伴有高热、呼吸障碍和吞咽困难时,医生应考虑到儿童咽部和咽间隙的这些解剖特征及其致病因素。然而,不应忘记在4岁以后出现不典型临床症状的咽后脓肿的频率较低但可能发生的情况。生物医学伦理委员会的BSMU乌克兰卫生部(Chernivtsi)确定研究按照“规则涉及人类受试者的医学研究伦理原则科学”经赫尔辛基宣言(1964 - 2013),我GCP(1996),监管(欧盟)609号1986年11月24日,乌克兰卫生部和订单690号23 2009年9月,2009年12月14日944号,616号,2012年8月3日。本文所提供的材料可建议出版(23年5月18日第7号议定书)。
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