Frontline Management of Advanced Epithelial Ovarian Cancer: A Comprehensive Statement by an Expert Group from Middle East and North Africa Region

Current Womens Health Reviews Pub Date : 2022-10-21 DOI:10.2174/1573404819666221021091708

H. Azim, O. Ozyılkan, Mudieddine Seoud, Amal Ladjeroud, H. Jaafar, M. Mokhtar, S. Alkhayyat, S. Dawood, Zafir Arik

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Abstract

Worldwide, ovarian cancer (OC) is one of the leading causes of cancer-related death among women. Despite the recent progress in the treatment of advanced OC, oncologists in many parts of the world still face several difficulties and constraints in their daily management of their patients. In addition to the shortage of resources and expertise, non-adherence to the up to date international guidelines has been identified as a major obstacle towards the improvement of treatment outcomes in the majority of developing countries, including the Middle East and North African (MENA) countries. A multidisciplinary gynecological oncology panel from the MENA region met virtually in December 2020 to discuss the challenges and hurdles faced by the community oncologists in the management of advanced OC. This manuscript reviews the key molecular and clinical studies that shaped the current international guidelines and suggests several modifications to make them more adaptable to the health status of developing countries of this region

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晚期上皮性卵巢癌的一线管理:中东和北非地区专家组的综合声明

在世界范围内，卵巢癌(OC)是妇女癌症相关死亡的主要原因之一。尽管最近在晚期OC的治疗方面取得了进展，但世界许多地区的肿瘤学家在日常患者管理中仍然面临一些困难和限制。除了缺乏资源和专门知识外，不遵守最新的国际准则已被确定为大多数发展中国家(包括中东和北非国家)改善治疗结果的主要障碍。来自中东和北非地区的多学科妇科肿瘤学小组于2020年12月举行了虚拟会议，讨论社区肿瘤学家在晚期卵巢癌管理中面临的挑战和障碍。本文回顾了形成当前国际指南的关键分子和临床研究，并提出了一些修改建议，使其更适应本地区发展中国家的健康状况

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Current Womens Health Reviews

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