Study of Optical Power Variations in Multi-layer Human Skin Model for Monitoring the Light Dose

2019 Novel Intelligent and Leading Emerging Sciences Conference (NILES) Pub Date : 2019-10-01 DOI:10.1109/niles.2019.8909332

Omnia Hamdy, Tawfik Ismail

{"title":"Study of Optical Power Variations in Multi-layer Human Skin Model for Monitoring the Light Dose","authors":"Omnia Hamdy, Tawfik Ismail","doi":"10.1109/niles.2019.8909332","DOIUrl":null,"url":null,"abstract":"Monitoring light dose is essential in much clinical procedures like bio-stimulation, neuro-medicine and photodynamic therapy and in many biophotonics applications such as optogenetics and biosensing. However, monitoring the optical power dissipation as light travels in different layers of tissue is essential in determining the required optical dose. Each part in the human body is protected by different thickness of skin layer; therefore, studying the variations of the optical power when light propagates in different thicknesses of the human skin is essential for safe and accurate medical diagnostic and/or therapeutic procedure. In this work, optical power attenuation in two multi-layers human skin models at different laser wavelengths and power is investigated. The system is analyzed using MonteCarlo simulation for light propagation in biological tissues. The obtained results showed a maximum penetrated power at 1100 nm laser irradiation for the both investigated models, while, the minimum power was recorded at 1500 nm. In addition, the absorbance in each skin layer was calculated providing essential information for both diagnostic and treatment purposes.","PeriodicalId":330822,"journal":{"name":"2019 Novel Intelligent and Leading Emerging Sciences Conference (NILES)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2019 Novel Intelligent and Leading Emerging Sciences Conference (NILES)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/niles.2019.8909332","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 6

Abstract

Monitoring light dose is essential in much clinical procedures like bio-stimulation, neuro-medicine and photodynamic therapy and in many biophotonics applications such as optogenetics and biosensing. However, monitoring the optical power dissipation as light travels in different layers of tissue is essential in determining the required optical dose. Each part in the human body is protected by different thickness of skin layer; therefore, studying the variations of the optical power when light propagates in different thicknesses of the human skin is essential for safe and accurate medical diagnostic and/or therapeutic procedure. In this work, optical power attenuation in two multi-layers human skin models at different laser wavelengths and power is investigated. The system is analyzed using MonteCarlo simulation for light propagation in biological tissues. The obtained results showed a maximum penetrated power at 1100 nm laser irradiation for the both investigated models, while, the minimum power was recorded at 1500 nm. In addition, the absorbance in each skin layer was calculated providing essential information for both diagnostic and treatment purposes.

查看原文本刊更多论文

用于监测光剂量的多层人体皮肤模型的光功率变化研究

光剂量监测在生物刺激、神经医学、光动力治疗等临床过程以及光遗传学、生物传感等生物光子学应用中都是必不可少的。然而，监测光在不同组织层中传播时的光功率耗散对于确定所需的光剂量至关重要。人体的每个部位都受到不同厚度的皮肤层的保护;因此，研究光在不同厚度的人体皮肤中传播时光功率的变化对于安全准确的医疗诊断和/或治疗程序至关重要。本文研究了不同激光波长和功率下两种多层人体皮肤模型的光功率衰减。利用MonteCarlo模拟光在生物组织中的传播，对该系统进行了分析。结果表明，两种模型在1100 nm激光照射下的穿透功率最大，而在1500 nm激光照射下的穿透功率最小。此外，计算每个皮肤层的吸光度，为诊断和治疗目的提供必要的信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

2019 Novel Intelligent and Leading Emerging Sciences Conference (NILES)

自引率

0.00%

发文量