[The role of bronchoalveolar lavage (BAL) in assessing pulmonary compromise in AIDS].

F Perna, A Sanduzzi, A Ponticiello
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Abstract

The severe immunologic alterations caused by HIV infection is at the base of respiratory tract infections, neoplasms and inflammatory complications which represent the most frequent cause of death in AIDS patients. The etiological diagnosis is difficult and often needs invasive procedures. Among those, BAL is surely the most useful method because of its lesser invasiveness and better tolerability and more for its sensibility and easier repeatability. Besides the etiological evaluation of lung infections, BAL allows to obtain and analyze immunologic and inflammatory cells from alveolar spaces consenting the acquisition of data regarding immunopathogenetic mechanisms related to pulmonary complications during AIDS. We report data about cytoimmunologic study of BAL fluid in 10 patients of ours.

[支气管肺泡灌洗(BAL)在评估艾滋病患者肺损害中的作用]。
艾滋病毒感染引起的严重免疫改变是呼吸道感染、肿瘤和炎症并发症的基础,这些是艾滋病患者最常见的死亡原因。病因诊断是困难的,往往需要侵入性手术。其中,BAL方法侵入性小,耐受性好,灵敏度高,可重复性好,是最有用的方法。除了肺部感染的病原学评估外,BAL还允许从肺泡间隙获取和分析免疫和炎症细胞,从而获得与艾滋病期间肺部并发症相关的免疫发病机制的数据。我们报告10例BAL液的细胞免疫学研究资料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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