Factors Leading to Intra Uterinegrowth Restriction in Termneonates

M. Usman, Kamil Ziad Rajper, J. Parkash, Ariba Fahim, Saeed Ahmed, Manoj Kumar
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Abstract

Background: The pathologic inhibition of intrauterine fetal growth and in capacity of fetus to develop to its full potential are both considered symptoms of intrauterine growth restriction. Nearly 10% of pregnancies experience impaired fetal growth. Since FGR was discovered to be a cause of neonatal death, approximately 50% of still births have been determined to be FGR, leading to a drop in unexplained still birth from 67–70% to 15%. A retrospective diagnosis of IUGR is made after the fact in roughly 75% of instances, compared to a detection rate of 15% in low-risk pregnancies. Objective: To assess the factors leading to Intra Uterine Growth Restriction among term neonates presenting to a National Institute of child health Karachi. Materials and Methods : A descriptive Cross-Sectional study was conducted at Department of Paediatrics of National Institute of child health Karachi from August2019 to February2020. Using a consecutive sampling method, 116 mothers were included in the study. Data was analyzed using SPSS version 23. Results: Mean age of the patient was 25.15 ±3.49 years. Mean weight, height, and BMI of the patients was 60.17±5.12kg,1.54±0.06 cm and 27.19 ±5.08kg/m2 respectively. Nulli parity was the most highest factor observed in 73 (63%) of the patients followed by low maternal BMI 64(55%), anemia 48(41%) and preeclampsia 37(32%). Conclusion: The finding of the study showed frequency of nulliparity was the found to be higher leading factor for IUGR followed by low maternal BMI, anemia, and preeclampsia among term neonates presenting to a tertiary care hospital. Keywords: Intra Uterine Growth Restriction, preeclampsia, low maternal BMI, anemia, nulliparity
导致胎儿宫内生长受限的因素
背景:病理性的宫内胎儿生长抑制和胎儿发育能力不足都被认为是宫内生长受限的症状。近10%的怀孕经历了胎儿生长受损。由于FGR被发现是新生儿死亡的一个原因,大约50%的死产被确定为FGR,导致不明原因的死产从67-70%下降到15%。在大约75%的病例中,IUGR的回顾性诊断是在事后进行的,相比之下,低风险妊娠的检出率为15%。目的:评价在卡拉奇国家儿童健康研究所就诊的足月新生儿中导致子宫内生长受限的因素。材料和方法:2019年8月至2020年2月在卡拉奇国家儿童健康研究所儿科进行了一项描述性横断面研究。采用连续抽样的方法,116名母亲被纳入研究。数据分析采用SPSS version 23。结果:患者平均年龄25.15±3.49岁。患者平均体重为60.17±5.12kg,身高为1.54±0.06 cm, BMI为27.19±5.08kg/m2。无胎次是73例(63%)患者中观察到的最高因素,其次是低母体BMI 64例(55%),贫血48例(41%)和先兆子痫37例(32%)。结论:本研究结果显示,在三级医院就诊的足月新生儿中,未生育频率是IUGR较高的主要因素,其次是母亲BMI低、贫血和先兆子痫。关键词:子宫内生长受限,先兆子痫,母体低BMI,贫血,不孕
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