[Immunohistochemically detected activity of lysozyme in sarcoidosis granulomas--a parameter for the activity of the illness process?].

H Eckert, I Sehrt, R Christ
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Abstract

In 30 patients with sarcoidosis we estimated immunohistochemically the activity of lysozyme in correlation to the activity of ACE in serum and found a positive correlation between these two parameters. We conclude, that the lysozyme content of sarcoidotic granulomas, estimated immunohistochemically, may be a useful morphological parameter of the activity of the disease, applicable on formol fixed and paraffin embedded bioptical material.

[免疫组织化学检测结节病肉芽肿溶菌酶活性——疾病过程活动性的参数?]
在30例结节病患者中,我们用免疫组织化学方法估计了溶菌酶活性与血清ACE活性的相关性,发现这两个参数之间呈正相关。我们的结论是,用免疫组织化学方法估计的结节样肉芽肿的溶菌酶含量可能是疾病活性的一个有用的形态学参数,适用于福尔摩固定和石蜡包埋的生物光学材料。
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