Biological Applications of Magnetic Nanoparticles; A Review

Shahana Khattak, Gul Rehman Elmi, Farah Azhar, Hina Ahsan, Kalsoom Saleem, Faryal Jahan
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Abstract

In nanotechnology field, iron oxide magnetic nanoparticles (IONPs) have gained much interest. The magnetic nanoparticles have been widely explored for applications due to ease of manufacturing and functionalization with polymers and other materials which makes them highly sensitive for many biological and biomedical applications. They transform electromagnetic energy into heat when exposed to magnetic field, and, hence, prove themselves as potent anti-cancer agent. The most advanced application of nanoscale materials towards human health is application as contrast agents in imaging modalities. MNPs proved safer as imaging contrast agents than conventional methods. MNPs have also been used in overcoming bacterial resistance and as anti-viral agent. They provide further evidences as emerging means in treatment and diagnosis of CVD and chronic inflammatory diseases like Rheumatoid arthritis. They also have employed in gene therapy to treat chronic diseases now a day.
磁性纳米颗粒的生物学应用研究回顾
在纳米技术领域,氧化铁磁性纳米颗粒(IONPs)受到了广泛的关注。磁性纳米颗粒由于易于制造和与聚合物和其他材料的功能化,使其对许多生物和生物医学应用具有高度敏感性,因此已被广泛探索应用。当暴露在磁场中时,它们将电磁能转化为热能,从而证明自己是有效的抗癌剂。纳米材料对人类健康最先进的应用是在成像模式中作为造影剂。MNPs作为成像造影剂被证明比传统方法更安全。MNPs也被用于克服细菌耐药性和抗病毒药物。它们为心血管疾病和风湿性关节炎等慢性炎症性疾病的治疗和诊断提供了进一步的证据。他们也在基因疗法中应用于慢性疾病的治疗。
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